ICE Effect. Cold that protects the bulbs.
Between extraction and implant, every follicle spends minutes outside the body. In those minutes, vitality decays. ICE Effect is the protocol that protects it.
Controlled temperature, biological integrity.
Once extracted, follicles are stored in a chilled saline solution at 4-8 °C in dedicated isothermal containers. Cold slows cellular metabolism, reduces oxidative stress, and maintains hydration of peri-bulbar structures until implant.
ICE Effect is not a machine — it's a protocol. It covers the entire ex vivo phase, from donor zone to recipient channel.
Hartmann's solution or HypoThermosol enriched with ATP and antioxidants.
Beyond this limit, even with ICE Effect, vitality drops. We work in single sessions.
Measured in internal studies on 240 consecutive patients (2024 – 2025).
ICE Effect works regardless of implant technique. Temperature is managed at extraction.
What changes versus standard protocol.
The difference isn't visible in the operating room — it shows later. Faster regrowth, attenuated shock loss, denser coverage at month 12.
Cell vitality
Progressive 5 – 15% drop in the first 2 ex vivo hours.
Negligible drop (<2%) even past 3 hours.
Oxidative stress
Free radicals build up in peri-bulbar tissue.
Antioxidants in the solution neutralize radicals.
Hydration
Progressive bulb dehydration.
Iso-osmotic solution maintains water balance.
Survival rate
85 – 92% in standard centers.
97 – 99% measured on our patients.
An invisible detail that changes the result.
ICE Effect isn't marketing — it's a protocol we've used for four years. It doesn't cost the patient extra; it's part of the package. We describe it because those who understand the difference look for it.